产品货号:
Z25256
中文名称:
RGS22抗体
英文名称:
Anti-RGS22 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-RGS22 Antibody |
指标别名 | CT145,PRTD-NY2,Regulator of G-protein signaling 22,RGS22 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IF |
基因名称 | RGS22 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | RGS22 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human RGS22.The immunogen is located within amino acids 870 - 920 of RGS22. |
计算分子量 | 147kDa |
成分 | RGS22 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | RGS22 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain,termed the RGS domain,that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit.RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11,12,and 13 (GNA11,GNA12,and GNA13).While RGS22 has been postulated to play a role in spermiogenesis in the testis,it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis.Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells,suggesting that RGS22 may be a potential prognostic biomarker for metastasis. |
Uniprot ID | Q8NE09 |
基因名全称 | Regulator of G-protein signaling 22 |
蛋白名全称 | Regulator of G-protein signaling 22 |
推荐稀释比 | RGS22 antibody can be used for detection of RGS22 by Western blot at 1 ~ 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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